Correlation between SGPT Levels and Haemoglobin Levels on Patients with Hepatitis B at RSUD Haji Surabaya

Abstract

Hepatitis B is an infection caused by the hepatitis B virus that attacks the liver and can trigger acute and chronic disease with a prevalence of 21.8% in Indonesia and can even cause death. Hepatitis B virus can cause liver inflammation that triggers cell damage and makes SGOT and SGPT enzymes in the liver release into the bloodstream. Damage to liver cells also leads to increased synthesis of hepcidin which functions to transfer iron to the systemic circulation. Reduced iron will lead to reduced haemoglobin levels in the body. This study is to see the correlation between SGPT levels and haemoglobin levels in patients with hepatitis B at RSUD Haji Surabaya. This type of research is descriptive with a sample size of 60 hepatitis B patient data. This study used secondary data from the clinical pathology laboratory of RSUD Haji Surabaya in December 2023 - May 2024. This study shows that from the data of 60 patient samples conducted statistical tests using the chi square test, it was found that there was no correlation between SGPT levels and haemoglobin levels in patients with hepatitis B with a significant value (p) of 0.189 > 0.05. There is no correlation between SGPT levels and haemoglobin levels in patients with hepatitis B.