Organoleptic of Pulp Capping Paste-Based Casein and Lactoferrin Cow's Milk

Abstract

Introduction: Pulp capping is a caries treatment, so teeth withstand for a long time in the oral cavity. The pulp capping material is expected to not only stimulate the mineralization of the pulp tissue to form reparative dentin in the various area, but it might be able to adhere and stay for a long time in dental tissues. Casein Cow's milk has a protein content that can stimulate the remineralization of dentin. Purpose: Testing the properties of a paste formulation based on casein and cow's milk lactoferrin. Methodology/Approach:  Evaluation of dental fillings in the form of pastes made from casein (20.450 gram/liter) and cow's milk lactoferrin (160.370 gram/liter) using the organoleptic test, homogeneity test, spread-ability test, and adhesion test. The ratio used between lactoferrin and casein is 8: 1. The formulations used include F1 (5% Carbopol, 40% ZnO, 2% TiO2, and 20% silica, Ph buffer 6.8), F2 (5% Carbopol, 40% ZnO, 2% TiO2, and 20% silica, 10% PVP, Ph buffer 6.8), F3 (5% Carbopol, 40% ZnO, 2% TiO2, and 20% silica, Eydragit RL 100 10%, Ph 6.8 buffer), F4 ( Carbopol 5%, ZnO 40%, TiO2 2%, and silica 40%, Eydragit RL 100 10%, Dapar Ph 6.8), F5 (Carbopol 5%, ZnO 20%, TiO2 2%, and silica 40%, PVP 10%, Buffer Ph 6.8). Findings: This research shows that there are 5 (five) formulations of pulp-capping paste ingredients. Each formulation of pulp capping paste had different average adhesion, spread, pH, and viscosity (p<0.05). Formulation V has the highest adhesion and spread among other formulations. FI, FIV, and FV toothpaste preparations had the lowest pH among the other groups. However, formulation II showed the best viscosity compared to the other groups. Conclusion: Formulations based on comparing the basic ingredients of casein-lactoferrin in cow's milk with additives having different physicochemical properties.